Full disclaimer, this is a pet peeve of mine. Not sure I can make a technical argument of why it matters. It is cleaner and prettier, feels let cluttered and so on. I even think it is a simple best practice for your small business internal CRM. But, when I jump in to a new CRM org it drives me nuts when the publisher is still defaulting and the org prefix is “new_”.
To change this is so easy, no real reason not to change it. I typically will just change it to some sort of abbreviated name of the client, or test or something.
In Dynamics CRM navigate to Settings->Customization->Publishers. Find the one that says “new” in the prefix column. Open and change.
End of pet peeve.